Dravet Syndrome (DS) is most often caused by heterozygous loss-of-function mutations in the voltage-gated sodium channel gene SCN1A (Nav1.1), resulting in severe epilepsy and neurodevelopmental impairment thought to be cause by reduced interneuron discount greenery excitability.However, recent studies in mouse models suggest that interneuron dysfun
The purpose of this work is to analyze the distribution of bulk materials according to the characteristic parameters of the mixing process at the second stage of processing in a rotary apparatus.The design of the rotary device has a wide range, including for the needs of agriculture, for example, when forming mixtures of mineral fertilizers and mul
Sulfate is the predominant electron acceptor for anaerobic oxidation of methane (AOM) in marine sediments.This process is carried out by a syntrophic consortium of anaerobic methanotrophic archaea (ANME) and sulfate reducing bacteria (SRB) through an energy conservation mechanism that is still poorly understood.It was previously hypothesized that f
The scale and nature of the impact of the imperial residence in St.Petersburg on the urban environment of the city center are considered.It is noted that St.Petersburg was a residence city for two centuries, which significantly affected its development.It is emphasized that the Winter Palace was not considered the center of city-planning compositio